Thursday, August 19, 2021

Watchman Report Aug. 19, 2021 "Is Anti Body Dependent Enhancement (ADE) A Looming Catastrophe?"

 


An explanation from Dr. Rhonda Patrick sheds more light on Antibody-dependent enhancement, or ADE. ADE is a phenomenon that occurs when low quality, low quantity, non-neutralizing antibodies bind to virus particles and, rather than neutralizing the virus, increase inflammation and tissue injury. ADE is a concern for scientists studying the SARS-CoV-2 virus. Other coronaviruses such as SARS-CoV-1 and MERS-CoV exhibit ADE. Many factors determine whether antibodies will neutralize a virus and protect the host or cause ADE and produce acute inflammation. These factors include antibody specificity, concentration, affinity, and isotype. In this clip, Dr. Rhonda Patrick discusses how inadequate antibody quantity and quality might lead to negative outcomes. Watch Dr. Patrick's YouTube clip below.

https://youtu.be/6CzdXyM00MA

The Looming Catastrophe - Anti body Dependent Enhancement detected with COVID-19

13 AUGUST 2021  

Peoplr who have been VACCINATED against COVID-19 are now subject to Antibody-Dependent Enhancement (ADE) which is likely to kill them. 

This is the absolute worst-case scenario with any vaccine.  People who took the vax should be quarantined immediately.

The "Journal of Infection" is a monthly peer-reviewed medical journal in the field of infectious disease, covering microbiology, epidemiology and clinical practice. Established in 1979, the journal was initially published quarterly by Academic Press and its first editor was Hillas Smith.  

The Journal possesses cutting-edge information for Doctors specializing in Infectious Diseases.  It is considered a "must read" each month by Infectious Disease Specialists.

On August 9, The Journal of Infection published a peer-reviewed study titled:

“Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants.” A potential risk for mass vaccination

This study revealed the terrifying news to the world:

ADE infection is a safety concern for vaccine strategies. In a recent publication the Journal of Infection (Li et al. Cell 184 :1-17, 2021) reported that infection-enhancing antibodies directed against the N-terminal domain (NTD) of the SARS-CoV-2 spike protein facilitate virus infection in vitro, but not in vivo. However, this study was performed with the original Wuhan/D614G strain.

Since the Covid-19 pandemic is now dominated with Delta variants, scientists analyzed the interaction of facilitating antibodies with the NTD of these variants.

Using molecular modelling approaches, we show that enhancing antibodies have a higher affinity for Delta variants than for Wuhan/D614G NTDs. We show that enhancing antibodies reinforce the binding of the spike trimer to the host cell membrane by clamping the NTD to lipid raft microdomains.

This stabilizing mechanism may facilitate the conformational change that induces the de-masking of the receptor binding domain. As the NTD is also targeted by neutralizing antibodies, our data suggest that the balance between neutralizing and facilitating antibodies in vaccinated individuals is in favor of neutralization for the original Wuhan/D614G strain.

However, in the case of the Delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity.

Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors).

Antibody Dependent Enhancement (ADE) is every virologist’s worst nightmare. It means the vaccine does the opposite of what was intended.

"In ADE, sub-optimal antibodies bind to both viruses and gamma receptors expressed on immune cells, then promoting infection of these cells."  In other words, your immune cells themselves become infected and carry the virus.

Vaccinated antibodies will be a trojan horse that gives the virus entry into cells, all cells of the body, the whole human body.

We will see massive sickness and death within the vaccinated population. Boosters will likely make the situation even worse.

Quote: “ Thus, ADE may be a concern for people receiving vaccines based on the original Wuhan strain spike sequence (either mRNA or viral vectors).” Translation: The shot makes a subsequent Infection “strikingly” worse (their words) and everybody was vaxxed using the original strain.

Quote: “ the possibility of ADE should be further investigated as it may represent a potential risk for mass vaccination during the current Delta variant pandemic.” Further investigated. Yeah right... when? By whom?  The same Quacks, like Fauci,  that gave us all this trouble in the first place?

Quote: “ Since the Covid-19 pandemic is now dominated with Delta variants.”

So ... this is a “concern” for anyone taking the first shot (actually everyone) as mass vax is a risk for the Delta variant which is now the dominant variety.

The world now has the worst case pandemic scenario.  We have it because of the vaccine.

It is almost laughable that the study authors say a second, different vax should be developed.   Well . . . . after many of the people who took Vax 1.0 are dead from ADE, do they really think anyone, anywhere, will trust them with Vax 2.0?

Below is a screen shot of the entire study in case someone decides to hide it.   A direct link to the study on the original web site is HERE

Bottom Line: People who got the vaccine, when they encounter the virus in real life, will not likely survive because their own immune system becomes infected and carries the disease absolutely everywhere in their body.  The immune system itself becomes the actual viral carrier.

 


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